| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.981 | 162 | 2 | 1995 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.934 | 151 | 3 | 1991 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 0.956 | 114 | 2 | 1999 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.400 | None | 0.967 | 91 | 3 | 2001 | 2020 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
disease | 0.400 | None | 0.956 | 90 | 3 | 2004 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 0.984 | 62 | 4 | 1993 | 2020 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.100 | None | 1.000 | 31 | 2 | 2013 | 2020 | ||||||||
|
BTB domain containing 8 | 0.547 | 0.692 | 6.1E-07 |
|
disease | 0.100 | None | 1.000 | 29 | 0 | 2004 | 2020 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
disease | 0.100 | None | 1.000 | 29 | 3 | 2003 | 2020 | ||||||||
|
triggering receptor expressed on myeloid cells 1 | 0.515 | 0.808 | 6.3E-03 |
|
disease | 0.100 | None | 0.920 | 25 | 2 | 2001 | 2020 | ||||||||
|
adrenomedullin | 0.436 | 0.808 | 4.1E-02 |
|
disease | 0.400 | None | 1.000 | 23 | 0 | 2000 | 2020 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.100 | None | 1.000 | 22 | 0 | 2011 | 2020 | ||||||||
|
angiopoietin 2 | 0.410 | 0.846 | 0.83 |
|
disease | 0.100 | None | 1.000 | 22 | 0 | 2008 | 2020 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.100 | None | 1.000 | 18 | 1 | 2001 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 18 | 0 | 2014 | 2020 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
disease | 0.100 | None | 1.000 | 17 | 0 | 2001 | 2020 | ||||||||
|
neutrophil migration | 0.473 | 0.808 |
|
disease | 0.100 | None | 0.938 | 16 | 0 | 2012 | 2020 | |||||||||
|
colony stimulating factor 3 | 0.377 | 0.885 | 0.38 |
|
disease | 0.400 | None | 1.000 | 15 | 0 | 2000 | 2020 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 2010 | 2020 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 13 | 0.496 | 0.769 | 5.1E-15 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2006 | 2020 | ||||||||
|
microRNA 21 | 0.363 | 0.846 |
|
disease | 0.100 | None | 1.000 | 12 | 1 | 2011 | 2020 | |||||||||
|
toll like receptor 9 | 0.411 | 0.885 | 9.8E-06 |
|
disease | 0.100 | None | 0.917 | 12 | 1 | 2009 | 2020 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.400 | None | 1.000 | 11 | 0 | 2005 | 2020 | ||||||||
|
von Willebrand factor | 0.408 | 0.885 | 3.2E-25 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2010 | 2020 | ||||||||
|
gasdermin D | 0.641 | 0.692 | 1.1E-13 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2017 | 2020 |